Detalhe da pesquisa
1.
Insights from a pharmacometric analysis of HDMTX in adults with cancer: Clinically relevant covariates for application in precision dosing.
Br J Clin Pharmacol
; 89(2): 660-671, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35998099
2.
Clinical implementation of pharmacogenetics and model-informed precision dosing to improve patient care.
Br J Clin Pharmacol
; 88(4): 1418-1426, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32529759
3.
Synthesis and PGE2 inhibitory activity of novel diarylheptanoids.
Bioorg Med Chem Lett
; 28(3): 334-338, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29290543
4.
Assessment of Dosing Strategies for Pediatric Drug Products.
Clin Pharmacol Ther
; 2024 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38493367
5.
CYP2D6 Phenotype Influences Pharmacokinetic Parameters of Venlafaxine: Results from a Population Pharmacokinetic Model in Older Adults with Depression.
Clin Pharmacol Ther
; 115(5): 1065-1074, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38284409
6.
Effects of obesity on the pharmacology of proton pump inhibitors: current understanding and future implications for patient care and research.
Expert Opin Drug Metab Toxicol
; 19(1): 1-11, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36800927
7.
Escitalopram and Sertraline Population Pharmacokinetic Analysis in Pediatric Patients.
Clin Pharmacokinet
; 62(11): 1621-1637, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37755681
8.
Tutorial on model selection and validation of model input into precision dosing software for model-informed precision dosing.
CPT Pharmacometrics Syst Pharmacol
; 12(12): 1827-1845, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37771190
9.
Clinical covariates that improve the description of high dose methotrexate pharmacokinetics in a diverse population to inform MTXPK.org.
Clin Transl Sci
; 16(11): 2130-2143, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37503924
10.
SLCO1B1 *15 allele is associated with methotrexate-induced nausea in pediatric patients with inflammatory bowel disease.
Clin Transl Sci
; 15(1): 63-69, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34423897
11.
Systematic Review of Pharmacogenetic Factors That Influence High-Dose Methotrexate Pharmacokinetics in Pediatric Malignancies.
Cancers (Basel)
; 13(11)2021 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34200242
12.
Toward pharmacogenetic SLCO1B1-guided dosing of methotrexate in arthritis using a murine Slco1b2 knockout model.
Clin Transl Sci
; 14(6): 2267-2277, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34121338
13.
MTXPK.org: A Clinical Decision Support Tool Evaluating High-Dose Methotrexate Pharmacokinetics to Inform Post-Infusion Care and Use of Glucarpidase.
Clin Pharmacol Ther
; 108(3): 635-643, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32558929